The subject of video games and its target audience seems to have become very convoluted over the years. Although still mainly a "guy thing", more and more females are getting into gaming. A lot more than when the first Ataris, Colecos, and Nintendo Entertainment Systems became popular.
According to the research group NPD, 44% of US-based gamers are female*. That's a huge jump. It's also a spit in the face of the Michigan State University study** from July that said women have less time to game than men do. Despite that, it does seem like I run into more women my age that play games in some form than I did about ten years ago, and frankly I'm impressed (not to mention ecstatic.)
I grew up with my dad and my brother, so I was surrounded by testosterone and lots of 'guy' things which included video games, womanizing, horror movies, and grunge music. I enjoyed every second of it and I'm certainly aware of how much interacting with my brother and his friends shaped me into the open-minded 25-year-old I am today.